A systematic review of PTSD to the experience of psychosis: prevalence and associated factors

Abstract Background Psychosis can be a sufficiently traumatic event to lead post-traumatic stress disorder (PTSD). Previous research has focussed on the trauma of first episode psychosis (FEP) and only review date PTSD beyond period was not systematic is potentially outdated. Methods We searched electronic databases reference lists using predetermined inclusion criteria retrieve studies that reported prevalence rates associated factors psychosis-related across all stages course psychosis. Studies were included if they measured specifically related experience Risk bias assessed an adapted version Newcastle Ottawa Scale. Results synthesised narratively. Six papers met criteria. Prevalence estimates varied from 14 47%. either first-episode samples or did specify number episodes experienced. Depression consistently with PTSD. Other potential associations treatment-related factors, severity, childhood trauma, individual psychosocial reactions trauma. Conclusions Psychosis-related common problem in people There lack published this Further needed larger, more generalizable samples. Our results tentatively suggest have reduced over past decade despite ambitions provide trauma-informed care. Prospero registration number: CRD42019138750.